Categories Game Guides

Operation: Plague Star guide – Warframe

Warframe’s Operation: Plague Star provides a unique opportunity to acquire vital materials, particularly pre-crafted Forma essential for upgrading equipment. Participants confront an extraterrestrial Infested menace threatening Cetus.

Operation: Plague Star guide – Warframe

Infested forces overwhelm Cetus’ open plains, centering around a massive biological growth. Utilizing stolen toxins from Vay Hek, combatants inject the infestation, battle emerging threats, and secure rewards through Operational Standing exchanges with Nakaka.

Mission Difficulty Levels

Mission tiers for Operation Plague Star

Three challenge levels accommodate various experience thresholds:

  • Standard Tier – Accessible entry level requiring no special items
  • Enhanced Tier – Demands Eidolon Phylaxis and Infested Catalyst
  • Elite Tier – Requires Steel Path clearance and both special components

Obtain Thrax Toxin

Infiltrate cave networks beneath the plains to secure Vay Hek’s biological agent. Mobility-enhanced Warframes significantly expedite toxin retrieval operations.

Toxin Preparation Process

Toxin mixture preparation

Combine stolen toxins at designated facilities while repelling Grineer counterattacks. Successful defense yields enhanced rewards through strategic component application.

  • Eidolon Phylaxis – Acquired through event progression rewards
  • Infested Catalyst – Crafted from Clan Dojo blueprints

Escort armored drones to infestation sites using spatial manipulation tactics while maintaining defensive formations during transit.

Final Eradication Phase

Hemocyte confrontation

Eliminate Infested masses while engaging progressively more formidable Hemocyte variants at higher tiers. Focus firepower on vulnerable biological weak points during attack patterns.

Event Rewards Structure

Progression through Operational Supply ranks unlocks premium crafting components and equipment blueprints, with Forma being particularly valuable for gear enhancement.

Champion 10 Nistlepod, 20000 Credits, 3000 Standing 0 to 494000
Defender 10 Iradite, 1000 Credits, 2000 Standing 0 to 3000
Collaborator 10 Grokdrul, 5000 Credits, 1000 Standing 0 to 2000
Neutral 0 0 to 1000
Aspirus APex Ephemera Champion 5000 Standing and 10000 Credits
Aspirus Emergent Ephemera Champion 4000 Standing and 8000 Credits
Aspirus Ephemera Champion 3000 Standing and 5000 Credits
Omni Forma Champion 5000 Standing and 10000 Credits
Plague Kripath Blueprint Champion 2000 Standing and 3500 Credits
Plague Bokwin Blueprint Champion 2000 Standing and 3500 Credits
Plague Keewar Blueprint Champion 2000 Standing and 3500 Credits
Plague Akwin Blueprint Champion 2000 Standing and 3500 Credits
Butcher Revelry (Mod) Champion 3000 Standing and 3500 Credits
Ghoulsaw Grip Blueprint Champion 4000 Standing and 3500 Credits
Ghoulsaw Engine Blueprint Champion 4000 Standing and 3500 Credits
Ghoulsaw Chassis Blueprint Champion 4000 Standing and 3500 Credits
Ghoulsaw Blade Blueprint Champion 4000 Standing and 3500 Credits
Ghoulsaw Blueprint Champion 4000 Standing and 1500 Credits
Exodia Epidemic (Arcane) Defender 5000 Standing and 1500 Credits
Exodia Contagion (Arcane) Defender 5000 Standing and 1500 Credits
Ether Daggers Blueprint Collaborator 3000 Standing and 5000 Credits
Snipetron Blueprint Collaborator 3000 Standing and 5000 Credits
Eidolon Phylaxis Blueprint Collaborator 2000 Standing and 4000 Credits
Forma Neutral 3000 Standing and 5000 Credits
Sacrifice Neutral 1500 Standing and 3500 Credits
Fulmination Neutral 1500 Standing and 3500 Credits
Cuthol Tendrils Neutral 750 Standing and 1500 Credits
Norg Brain Neutral 750 Standing and 1500 Credits
Murkray Liver Neutral 750 Standing and 1500 Credits
Heart Nyth Neutral 750 Standing and 1500 Credits
Radian Sentirum Neutral 750 Standing and 1500 Credits
Cetus Wisp Neutral 750 Standing and 1500 Credits
Plague Star Emblem Neutral 500 Standing and 1000 Credits
Fosfor Rahd Blueprint Neutral 250 Standing and 500 Credits
Fosfor Blau Blueprint Neutral 250 Standing and 500 Credits