Poison builds dominate late-game MegaBonk by combining area damage, mobility, and persistent effects. Key strengths include:

• Scaling damage over time
• Passive crowd control
• Synergy with survivability mechanics

Core Poison Build Mechanics

This strategy revolves on three pillars:

• Proc chance enhancement
• Poison spread optimization
• Sustain through defensive upgrades

Top Poison-Compatible Characters

• Amog: Generates poison explosions on enemy deaths (best pure poison specialist)
• Sir Oofie: Tanky framework lets poison work while absorbing damage
• Athena: Hybrid thorn/poison synergy for durable alternative builds

Optimal Weapon Pairings

• Aura: Constant proximity-based poisoning
• Bone: Multi-target projectile contamination
• Lightning Staff: Crowd control extension for poison’s delayed damage

Essential Tomes

• Damage: Amplifies poison tick values
• Attack Speed: Increases status application frequency
• Quantity: Wider area coverage
• Regen: Sustain during poison ramp-up

Must-Have Items

• Moldy Cheese: Core poison application engine
• Moldy Gloves: Adds poison cloud area denial
• Toxic Barrel: Retaliatory poison waves when damaged
• Gas Mask: Converts poisoned enemies into lifesteal/armor sources
• Overpowered Lamp: Maximizes proc consistency

Progression Strategy

• Early Game: Prioritize defense (Regen/Armor tomes)
• Mid Game: Acquire poison items, then focus on attack speed/projectile count
• Boss Fights: Kite while maintaining poison stacks
• End Game: Combine Gas Mask with defensive tomes for stationary wave-clearing

FAQs

• Moldy Cheese unlock: Complete specific quest for permanent access
• Damage Tome synergy: Directly boosts poison effectiveness
• Amog’s superiority: Passive explosions create multiplicative damage
• Gas Mask synergy: Turns poison into both offense and defense