Hades 2 equippable items called Keepsakes offer strategic advantages at the beginning of each escape attempt. These gifts earned through nectar exchanges can be enhanced over time. Below we explore various trinkets and their optimal applications within your journey through the underworld.

Initial Crafted Relics

Hecate’s Celestial Orb provides 100 arcane energy at run commencement, ideal for spellcasters but often substituted during progression. Odysseus’ Combat Fragments decrease boss vitality by 15% while providing 10% damage mitigation, proving valuable during major confrontations.

Mortal Revival Charm by Schelemus grants a single resurrection to 101 HP per cycle, particularly advantageous during initial ascents. Spectral Bulb from Dora fully restores vitality upon exiting zones (max 100 nightly), supplementing sustain capabilities. Vengeful Gaze from Nemesis amplifies damage by 30% against previously vanquished foes, enhancing boss combat efficiency.

Strategic Support Charms

Charon’s Coin Pouch offers bonus currency, synergizing with commerce-focused builds like Poseidon’s wealth-oriented blessings. Moros’ Fate Seal provides temporary invulnerability upon critical health, demanding rapid enemy elimination within 10 seconds. Successful execution restores 60 HP, presenting high-risk tactical advantages.

Eris’ War Chime gradually increases offensive capabilities by 1% per cleared arena while amplifying incoming damage identically. This calculates risk-reward balance, particularly when combined with defensive Arcana enhancements. Hermes’ Velocity Shard boosts movement and attack speeds by 20% for limited durations, complementing agility-centric playstyles.

High-Stakes Empowerment

Artemis’ Primal Horn grants 30% critical chance while limiting maximum HP to 30, demanding flawless play execution. Selene’s Lunar Nexus activates stellar augmentation paths for cosmic abilities, primarily benefiting hex-focused configurations. Dionysus’ Skip Card occasionally nullifies enemy spawns across three biomes, providing temporary combat respite.

Protective Artifacts

Arachne’s Barrier Thread grants 30 additional armor points if already shielded, accumulating four per cleared zone – ideal for defense-oriented builds. Narcissus’ Amplification Flask enhances restorative pools by 20% and elevates random buff quality nightly, valuable for prolonged expeditions.

Combat Accelerators

Echo’s Enhancement Core provides 75% chance for bonus upgrade opportunities nightly. Heracles’ Predator Mark delivers 50% initial damage buff decaying per strike, optimized for elite engagements. Medea’s Retaliation Mantle amplifies special attacks by 40% after sustaining 250 damage, rewarding aggressive tactical positioning.

Arcana Manipulators

Circe’s Celestial Effigy activates dormant Arcana cards post-boss defeats, synergizing with judgment-based card effects to multiply strategic options. Icarus’ Developmental Anvil randomly grants weapon modifers for 20 encounters, introducing combat variability. Chaotic Seed provides random primordial blessings every eight cleared zones, offering unpredictable power spikes.

Divine Favor Tokens

Olympian deities provide boon-influencing relics like Zeus’ Storm Band alongside offerings from other major gods. Athena’s Resilience Laurel ensures epic-quality blessings when devoid of revival chances, aligning with survival-focused Arcana combinations.

Premier Non-Deity Equipment

Predator Mark offers substantial initial damage output while Enhancement Core accelerates early-game progression. Vengeful Gaze specializes in prioritized target elimination, with Revival Charm proving crucial during initial ascension phases. Discordant equipment balances power amplification with increased vulnerability, demanding precise combat execution.