Selecting the optimal class in Borderlands 4 hinges on combat preferences and tactics for overcoming enemies. The four playable Vault Hunters – Rafa, Vex, Harlow, and Amon – each offer distinct abilities demanding strategic builds for maximum effectiveness.
Class Rankings and Playstyles
While personal preference dictates your ideal class, these recommendations cater to different player archetypes:
- New players: Vex’s health regeneration mechanics and companion system create forgiving combat experiences
- Series veterans: Harlowe and Rafa reward precision aiming and tactical positioning in firefights
- Solo adventurers: Vex’s AI allies and Amon’s defensive capabilities ensure survival in isolation

Optimized Vex Configuration
The Blood Letter specialization maximizes critical damage potential through precise aiming. Combine Dead Ringer action skills with bleed-inducing weaponry to cripple enemy forces. Prioritize kinetic damage modifiers and critical chance enhancements across gear selections.




Superior Harlowe Setup
Focus on CHROMA Accelerator’s radiation output through the Creative Bursts skill tree. Combine rapid-fire weapons with cooldown reduction enhancements to maintain constant elemental pressure. Neutron Capture augment transforms stored energy into devastating radiation bursts.
Dominant Rafa Loadout
The Ricochet build leverages Jakobs weaponry for projectile deflection strategies. Distribute skill points across El Valiente enhancements and Lateral Plinking mechanics. Peacebreaker Cannons with Instinto augment create lethal critical strike chains against grouped enemies.




Premier Amon Configuration
Combine Cryo Ordnance mechanics with melee proficiency through the Scourge action skill. Balance Vengeance and Calamity skill trees to maximize area denial and close-quarters combat effectiveness. Prioritize frost-based enhancements and shield regeneration capabilities.
Character Breakdown
Vex: Phase Manipulator
Commands spectral allies while enhancing weapon lethality through critical modifiers
Harlowe: Elemental Strategist
Specializes in environmental control through radiation and temporal effects
Rafa: Ballistic Specialist
Masters shock-based artillery and projectile redirection tactics
Amon: Defensive Juggernaut
Employs frost augmentation and shield technology for frontline dominance



