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Abyssus Best Weapons & Guns Tier List

In Abyssus, choosing the right weapons can make or break your runs. This tier list evaluates all primary weapons based on endgame viability, room-clearing efficiency, and boss-killing potential.

Pro Tip: Discover weapon unlock methods here

Top Weapons at a Glance

  • S TierTesla Gun, Combat Bow, Plasma Launcher
  • A TierRevolver, Fish Gun
  • B TierMachinegun, Shotgun, Plasma Cannon
  • C TierPistol, Burst Machinegun

S-Tier Breakdown

Tesla Gun

  • Dominates crowd control with chain lightning effects via Spark Orbs
  • Synergizes with elemental effects for area denial

Combat Bow

  • High crit density enables rapid-fire builds
  • Pairs exceptionally with barrier-based strategies

Plasma Launcher

  • Explosive potential escalates with projectile modifiers
  • Freeze combos amplify single-target burst damage

A-Tier Contenders

Brine Revolver

  • Undisputed boss killer with precision shot potential
  • Requires support items for crowd management

Fish Gun

  • Balances crowd control with quirky mechanics
  • Synergizes well with explosion-focused builds

Optimal Build Strategies

Plasma Launcher Combos

  • Fan Amulet + Mr. Boom Amulet creates multiplicative explosions
  • Freeze-triggered damage bonuses enhance boss melts

Turret Synergies

  • Barrier-focused upgrades enable safer bow/tesla gameplay
  • Requires dedicated investment to maximize utility

Cube Builds

  • Laser Cube + Ghost explosion mods create chain reaction nukes
  • Blood orbs add supplementary area damage

Ranking Methodology

  • Data compiled from Brine 15+ clears
  • Evaluated scaling with common trinket combinations
  • Prioritized weapons requiring minimal setup for maximum impact

FAQ

Best All-Around Weapon?

Tesla Gun for general use, Combat Bow for balanced play, Plasma Launcher for explosive specialists.

Top Single-Target DPS?

Revolver reigns supreme, though optimized Bow/Plasma builds can compete.

Are Turrets Viable?

Yes – Barrier turrets enable aggressive playstyles but require focused upgrades.